It's harder but we're still finding oil in Oklahoma today. The bar has been raised on startup companies but it can still be done. Every regulation and every rule limits you but yes it can still be done. That's the beauty of living in a free country and having the freedom to have an idea and become an entrepreneur.
Our bodies are shaped to bear children and our lives are a working out of the processes of creation. All our ambitions and intelligence are beside that great elemental point.