A guy is a lump like a doughnut. So first you gotta get rid of all the stuff his mom did to him. And then you gotta get rid of all that macho crap that they pick up from beer commercials. And then there's my personal favorite the male ego.
The weapons were conceived and created by a small band of physicists and chemists they remain a cataclysmic threat to the whole of human society and the natural environment.