The threat today is not that of the 1930s. It's not big powers going to war with each other. The ravages which fundamentalist political ideology inflicted on the 20th century are memories. The Cold war is over. Europe is at peace if not always diplomatically.
We humans are an extremely important manifestation of the replication bomb because it is through us - through our brains our symbolic culture and our technology - that the explosion may proceed to the next stage and reverberate through deep space.