There's the conventional wisdom of which I have none where you get a record deal you get a publicist you get a campaign and you do the tour but none of that adds up to things like nuance and subtlety and dynamic.
Like it or not in the end it's one's body. It's literally what carries you through life. There's a reason for the saying 'If you have your health you have everything ' and it's true. Old age disease - these are the great equalizers.