In a world that is constantly changing there is no one subject or set of subjects that will serve you for the foreseeable future let alone for the rest of your life. The most important skill to acquire now is learning how to learn.

Fear is that thing that keeps you up there on that other plateau. Fear is that thing that just keeps you closed down and quite frankly alone.

Should we find a second form of life right here on our doorstep we could be confident that life is a truly cosmic phenomenon. If so there may well be sentient beings somewhere in the galaxy wondering as do we if they are not alone in the universe.

The way life manages information involves a logical structure that differs fundamentally from mere complex chemistry. Therefore chemistry alone will not explain life's origin any more than a study of silicon copper and plastic will explain how a computer can execute a program.

For every five well-adjusted and smoothly functioning Americans there are two who never had the chance to discover themselves. It may well be because they have never been alone with themselves.

As I've gotten older I've occasionally found myself nostalgic for earlier periods of solitude though I realize that's also likely a false nostalgia as I know there was nothing I wanted more during those periods than to not be alone whatever that means.

But there is a discomfort that surrounds grief. It makes even the most well-intentioned people unsure of what to say. And so many of the freshly bereaved end up feeling even more alone.

A book is sent out into the world and there is no way of fully anticipating the responses it will elicit. Consider the responses called forth by the Bible Homer Shakespeare - let alone contemporary poetry or a modern novel.

But there's not enough time in life to go sit at a party have a drink and make idle conversation. There's too many important things to do. Just being together with my husband spending time alone which I have very little of.

I believe in capitalism for everybody not necessarily high finance but capitalism that works for the working men and women of this country who are out there paddling alone in America right now.

Glasgow's not a media center. When you're there when you're hanging about you feel quite detached from musical movements or fashions or anything like that. You do feel quite alone in a good way.

As the only girl growing up among three brothers I was always afraid of being excluded. If there was a game to be played a sport to be learned a competition to join I was on my feet and ready. I didn't spend much time alone for fear that I'd miss out.

There's nobody else on the face of this earth that's playing a sport at a highest level... with a transplant. That alone continues to inspire me because I realize throughout the whole world the struggles that people are going through. I need to inspire them the best way I can.

There's great sadness and life doesn't work out like you would want on a lot of levels but there's no need to feel all alone. This happens to everybody so there's no self-pity. This is the ride that humans are on and all of it is essential for our natural part of it.

If you're truly in a band and you guys have been together for a long time there's a family bond that you have. In fact I've talked about this with therapists especially if you're talking about a relationship because when you're with somebody you're going to your family and she's alone.

I hope this will help new moms not feel alone or desperate and that there is no shame in their feelings. PPD is out of their control but the treatment and healing process is not.

I tour alone. There's no sound check no back up. I stay with the hosts I am in a family home and it's really nourishing. I just have to remember after the show not to run out into the living room in my pyjamas. Every day it's a new relationship being built. It's odd and wonderful.

Very few people are original. There's very little original anything out there. Because to be original means you have to stand alone.

Once you grow past Mommy and Daddy coming running when you're hurt you're really on your own. You're alone and there's no one to help you.

Is there no Latin word for Tea? Upon my soul if I had known that I would have let the vulgar stuff alone.

With 'Twilight ' you have these massive tomes that you have to condense. With 'Penoza ' we had an eight episode Dutch series that just for the pilot alone I condensed three episodes. So there's a lot of filling in and a ton of invention that has to happen to fill out eight episodes.

I don't know that I spent any more time alone than any other kid but being by myself never bothered me.

It depends on the situation. I mean on one hand there's the argument that people should be left alone on the other hand there's the argument to wade in a stop slaughters in places like Bosnia and Kosovo and what we probably should have done in Rwanda.

We've just got to be careful - with all sports let alone cricket - I think there's so much emphasis on doing the right thing all the time but I think the public want to be entertained when they come to watch sport.